The observational study titled "DHEA Replacement in Women with Adrenal Insufficiency—Pharmacokinetics, Bioconversion, and Clinical Effects on Well-being, Sexuality, and Cognition" (Endocrine Research, 2000, PMID: 11196420) investigated the impact of DHEA supplementation on women with adrenal insufficiency. The study found that DHEA replacement therapy significantly improved well-being and sexual function, likely
