The article titled "Combination treatment with T4 and T3: toward personalized replacement therapy in hypothyroidism?" from the Journal of Clinical Endocrinology & Metabolism (2012, PMID: 22593590) reviews evidence on combination therapy with levothyroxine (T4) and liothyronine (T3) for hypothyroidism. While standard T4 monotherapy effectively normalizes TSH levels in most patients,
