This 2024 clinical study assessed the effectiveness of a topical antioxidant serum containing 0.5% silymarin, 15% L-ascorbic acid, 0.5% ferulic acid, and 0.5% salicylic acid in treating facial acne. In a 12-week Brazilian trial (n=56), the serum achieved a 45% reduction in inflammatory lesions and a 43% reduction in non-inflammatory