This 1985 review by Vance and Vance examines the critical role of phosphatidylcholine (PC) biosynthesis in the assembly and secretion of lipoproteins by hepatocytes. PC, a major phospholipid in plasma lipoproteins, is synthesized in the liver via two pathways: the CDP-choline (Kennedy) pathway and the phosphatidylethanolamine methylation pathway. The study
