Well Referenced

Tag: fatty liver

The role of phosphatidylcholine biosynthesis in the secretion of lipoproteins from hepatocytes

This 1985 review by Vance and Vance examines the critical role of phosphatidylcholine (PC) biosynthesis in the assembly and secretion of lipoproteins by hepatocytes. PC, a major phospholipid in plasma lipoproteins, is synthesized in the liver via two pathways: the CDP-choline (Kennedy) pathway and the phosphatidylethanolamine methylation pathway. The study

June 26, 2025 No Comments

Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms

This article reviews the crucial role of choline in maintaining liver function, focusing on how choline influences gene expression through epigenetic mechanisms like DNA and histone methylation. Choline is vital for generating S-adenosylmethionine, which regulates liver-related gene expression. A deficiency in choline can lead to liver issues such as fatty

June 26, 2025 No Comments