High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736)

This 2010 preclinical study by Ilic et al., published in the Journal of Physiology and Pharmacology, investigated the protective effects of the stable gastric pentadecapeptide BPC 157 against severe paracetamol-induced toxicity in rats. Administering a high hepatotoxic dose of paracetamol (5 g/kg intraperitoneally) led to rapid onset of generalized convulsions,