Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging

This study investigated the relationships between inflammatory markers, kynurenine pathway metabolites, B vitamins, age, and mortality in a cohort of 1,839 older adults. Results indicated that elevated levels of inflammatory markers and kynurenine pathway metabolites were associated with increased age and higher mortality risk. Conversely, higher concentrations of certain B