Nebulized glutathione induces bronchoconstriction in patients with mild asthma

This randomized, double-blind, placebo-controlled crossover study evaluated the effects of nebulized glutathione (GSH) on airway responsiveness in eight patients with mild asthma. While GSH is known for its antioxidant properties, nebulized administration (600 mg in saline) caused significant bronchoconstriction, with a 19% drop in FEV1 and a 61% increase in