Tag: Vitamin B12 deficiency

This 2016 review article examines the clinical utility of anti-parietal cell antibodies (APCA) in diagnosing autoimmune atrophic gastritis (AAG) and pernicious anemia (PA). APCA target the H+/K+ ATPase proton pump in gastric parietal cells, primarily the alpha subunit. Detection methods include immunofluorescence, ELISA, and radioimmunoprecipitation assay (RIA), with RIA offering