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Tag: VITAL trial

Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

The VITamin D and OmegA-3 TriaL (VITAL) was a randomized, placebo-controlled trial involving 25,871 U.S. adults (men ≥50 years, women ≥55 years) with no prior history of cancer or cardiovascular disease. Participants received either 2,000 IU/day of vitamin D₃ or placebo for a median of 5.3 years. The trial found

June 26, 2025 No Comments

Effect of Vitamin D3 Supplements on Development of Advanced Cancer: A Secondary Analysis of the VITAL Randomized Clinical Trial

This 2020 secondary analysis from the VITAL trial evaluated whether daily vitamin D3 supplementation (2000 IU) reduces the risk of developing advanced cancer (metastatic or fatal) among 25,871 cancer-free adults aged 50 years and older (men) and 55 years and older (women). While there was no significant reduction in total

June 26, 2025 No Comments