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Tag: urologic oncology

Prostate MRI versus PSA Screening for Prostate Cancer Detection (the MVP Study): A Randomised Clinical Trial

This 2023 randomized clinical trial (MVP Study) evaluated the comparative effectiveness of MRI versus prostate-specific antigen (PSA) screening in prostate cancer detection. The study included men aged 50–75 and randomized them to receive either MRI or PSA screening. MRI screening demonstrated superior detection of clinically significant prostate cancers (Gleason score

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June 26, 2025 No Comments

Role of Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer: Experience Over the Last Decade

This 2019 systematic review evaluated 13 studies involving 754 patients with muscle-invasive bladder cancer (MIBC) who received neoadjuvant chemotherapy with gemcitabine and cisplatin (GC) prior to radical cystectomy. The analysis demonstrated a complete pathological response (pT0) in 30% of patients and pathological downstaging to non–muscle-invasive disease (

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June 26, 2025 No Comments

The role of testosterone replacement therapy following radical prostatectomy

This review examined the potential role of testosterone replacement therapy (TRT) in hypogonadal men following radical prostatectomy for prostate cancer, challenging the historical contraindication due to concerns about cancer recurrence. Several studies reviewed showed that TRT did not significantly increase prostate-specific antigen (PSA) levels or lead to biochemical recurrence, with

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June 26, 2025 No Comments