Well Referenced

Tag: urinary incontinence

Functional and quality of life outcomes of localised prostate cancer treatments (Prostate Testing for Cancer and Treatment [ProtecT] study)

This large-scale longitudinal study assessed the functional and quality of life outcomes in 2,565 men aged 50–69 with localized prostate cancer, randomized to active monitoring (AM), radical prostatectomy (RP), external-beam radiotherapy (EBRT) with androgen deprivation therapy (ADT), or low-dose-rate brachytherapy (BT). Over six years, AM was associated with gradual declines

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June 26, 2025 No Comments

10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

This randomized controlled trial evaluated the long-term outcomes of monitoring, surgery, or radiotherapy in patients with localized prostate cancer. Over a 10-year period, the study found no significant differences in prostate cancer-specific mortality between the three treatment groups. However, surgery and radiotherapy were associated with higher rates of erectile dysfunction

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June 26, 2025 No Comments

Long-term quality of life in prostate cancer

The commentary discusses the long-term quality of life outcomes in prostate cancer patients, referencing the Prostate Cancer Outcomes Study (PCOS), which followed 1,655 men aged 55-74 years over 15 years. The study found significant declines in sexual, urinary, and bowel function across all treatment modalities. Erectile dysfunction was prevalent in

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June 26, 2025 No Comments

Radical prostatectomy versus observation for localized prostate cancer

This randomized controlled trial compared radical prostatectomy with observation in 731 men with clinically localized prostate cancer over a median follow-up of 10 years. The study found no significant reduction in all-cause mortality (47.0% vs. 49.9%; HR 0.88; 95% CI, 0.71–1.08; P=0.22) or prostate-cancer-specific mortality (5.8% vs. 8.4%; HR 0.63;

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June 26, 2025 No Comments