Observations on the Doubling Time of Prostate Cancer: The Use of Serial Prostate-Specific Antigen in Patients with Untreated Disease as a Measure of Increasing Cancer Volume
This 1993 study evaluated PSA doubling times (PSADT) in 43 patients with untreated prostate cancer over an average of 30 months. The findings demonstrated that PSA levels increased in a log-linear (exponential) fashion, with doubling times varying significantly based on tumor stage and grade. Patients with higher-stage and higher-grade tumors
June 26, 2025
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