Tag: Triple-Negative Breast Cancer

Recent Advances in Therapeutic Strategies for Triple-Negative Breast Cancer

This 2022 review comprehensively examines the latest therapeutic developments for triple-negative breast cancer (TNBC), a highly aggressive and heterogeneous subtype lacking hormone receptors and HER2 expression. The article outlines current treatment paradigms including chemotherapy, and highlights advancements such as immune checkpoint inhibitors (e.g., pembrolizumab, atezolizumab) for PD-L1-positive TNBC and PARP

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A Retrospective Study of Gemcitabine and Carboplatin With or Without Intravenous Vitamin C on Patients With Advanced Triple-Negative Breast Cancer

This retrospective study examines the effectiveness of combining gemcitabine and carboplatin chemotherapy with or without intravenous vitamin C in patients with advanced triple-negative breast cancer (TNBC). The results suggest that adding vitamin C to chemotherapy may improve treatment outcomes, with patients showing enhanced response rates and potentially reduced side effects.

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Association of statin use with clinical outcomes in patients with triple-negative breast cancer

This study investigates the impact of statin use on clinical outcomes in patients with triple-negative breast cancer (TNBC). The results suggest that statin use is associated with improved overall survival and progression-free survival in TNBC patients. The article explores the potential mechanisms, including statins’ effects on cholesterol metabolism and inflammation,

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