Contemporary perspectives on heterotopic ossification
This 2022 review explores the mechanisms and management of heterotopic ossification (HO), distinguishing between trauma-induced (tHO) and genetic forms like fibrodysplasia ossificans progressiva (FOP). The study highlights that both forms involve reactivation of developmental bone pathways, including intramembranous and endochondral ossification. Current prophylactic treatments include NSAIDs for tHO and glucocorticoids
June 26, 2025
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