Well Referenced

Tag: Testosterone replacement

Association of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism

This case-crossover study analyzed data from 39,622 men aged 57.4 years on average, using the IBM MarketScan and Medicare Supplemental databases (2011–2017). It assessed the short-term risk of venous thromboembolism (VTE) associated with testosterone therapy (TT) in men with and without hypogonadism. TT was linked to a significantly increased risk

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June 26, 2025 No Comments

Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men

The study “Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men” examined the effects of induced hypogonadism on sexual function and its relationship with cerebrospinal fluid (CSF) levels of neurosteroids and monoamine metabolites. In this comparative study, healthy male volunteers received the gonadotropin-releasing hormone agonist leuprolide acetate

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June 26, 2025 No Comments

Not just sex: other roles for testosterone in women

This article explores the role of testosterone in women, particularly postmenopausal women, and its therapeutic use in treating low sexual desire. Testosterone therapy has been shown to improve sexual function, but its broader benefits for other areas of women’s health remain uncertain. While testosterone replacement is effective for improving sexual

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June 26, 2025 No Comments

Cardiovascular Safety of Testosterone-Replacement Therapy

This study evaluated the cardiovascular safety of testosterone replacement therapy in men aged 45-80 with hypogonadism and cardiovascular risk. It found that testosterone therapy did not increase cardiovascular risk, showing noninferiority to the placebo. This research supports the safety of testosterone for long-term use in men with metabolic concerns and

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June 26, 2025 No Comments

Cognitive response to testosterone replacement added to intensive lifestyle intervention in older men with obesity and hypogonadism: prespecified secondary analyses of a randomized clinical trial

A randomized controlled trial published in the American Journal of Clinical Nutrition (PMID: 34375393) examined the effects of testosterone replacement therapy combined with intensive lifestyle intervention in older men with obesity and hypogonadism. The study included 83 participants who were randomly assigned to either a testosterone or placebo group for

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June 26, 2025 No Comments