This 2020 study investigated taurine’s antiallergic effects on allergic rhinitis (AR) through both in vitro and in vivo models. In AR patients, serum levels of extracellular superoxide dismutase (SOD3) were reduced. Taurine treatment increased SOD3 expression in human mast cells via activation of peroxisome proliferator-activated receptor-γ (PPAR-γ), leading to decreased
This 2021 study evaluated the effects of supplementing methionine and/or taurine in low-fishmeal diets for largemouth bass. Diets containing 14.5% fishmeal were supplemented with 0.5% methionine, 0.5% taurine, both, or neither. Results showed that methionine supplementation, alone or combined with taurine, significantly improved growth, feed efficiency, protein and lipid retention,
This preclinical study evaluated the neuroprotective effects of taurine in a rat model of sporadic Alzheimer’s disease induced by intracerebroventricular (ICV) injection of streptozotocin (STZ). Rats received a single bilateral ICV-STZ injection (3 mg/kg), leading to cognitive deficits, oxidative stress, and cholinergic dysfunction. Taurine was administered orally at 50 mg/kg
This 2023 study published in Science investigated the role of taurine, a semi-essential amino acid, in the aging process. Researchers observed that taurine levels decline with age in mice, monkeys, and humans. Supplementation of taurine in middle-aged mice increased lifespan by 10–12% and improved healthspan in monkeys. Mechanistically, taurine supplementation
This review article discusses the roles of sulfur-containing amino acids—methionine, cysteine, homocysteine, and taurine—in human biochemistry. Methionine, an essential amino acid, is involved in methylation reactions and protein synthesis, while cysteine plays a crucial role in protein structure and is the precursor for glutathione and taurine. The metabolism of homocysteine,
This article discusses the use of nutraceuticals like spirulina, taurine, pantethine, and lipoic acid to reduce the toxic effects of alcohol, particularly by alleviating oxidative stress and promoting the breakdown of acetaldehyde. Spirulina inhibits NADPH oxidase, which reduces oxidative damage, while taurine, pantethine, and lipoic acid enhance the activity of
