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Tag: TACT2

Chelation Therapy in Coronary Artery Disease: Fact or Fiction?

This 2025 review examines the efficacy of chelation therapy, specifically using ethylenediaminetetraacetic acid (EDTA), in treating coronary artery disease (CAD). While the 2013 Trial to Assess Chelation Therapy (TACT) indicated modest cardiovascular benefits, particularly in diabetic patients, subsequent studies like TACT2 did not confirm these findings. TACT2 demonstrated that although

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June 26, 2025 No Comments

The Trial to Assess Chelation Therapy 2 (TACT2): Rationale and Design

This article presents the design and rationale of the TACT2 trial, a randomized, double-blind, placebo-controlled study aiming to confirm the cardiovascular benefits of EDTA chelation therapy observed in diabetic patients in the original TACT trial. Targeting a high-risk population of 1,200 patients with diabetes and prior myocardial infarction, the trial

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June 26, 2025 No Comments