Well Referenced

Tag: survival outcomes

Prognostic Factors in Metaplastic Carcinoma of the Breast: A Multi-Institutional Study

This 2014 international multicenter study analyzed 405 cases of metaplastic breast carcinoma (MBC) to evaluate clinicopathological features and prognostic factors. The study found that lymph node status, lymphovascular invasion, and histologic subtype significantly influenced outcomes, whereas tumor size and grade did not. Notably, spindle cell carcinoma subtype was associated with

Read More »
June 26, 2025 No Comments

Endocrine therapy initiation and overall survival outcomes with omission of radiation therapy in older Medicare patients with early-stage hormone-receptor-positive breast cancer

This 2022 population-based study analyzed data from the SEER-Medicare database to assess endocrine therapy (ET) initiation and overall survival (OS) among women aged 70–90 with early-stage, hormone receptor-positive, HER2-negative breast cancer who underwent lumpectomy without radiation therapy between 2010 and 2015. Of 2,618 patients, 30.9% did not initiate ET. Logistic

Read More »
June 26, 2025 No Comments

Association between imaging surveillance frequency and outcomes following surgical treatment of early-stage lung cancer

This study examines the relationship between the frequency of imaging surveillance and clinical outcomes in patients who underwent surgical treatment for early-stage lung cancer. The results indicate that more frequent imaging surveillance is associated with earlier detection of recurrence, leading to improved survival outcomes. However, the study also highlights the

Read More »
June 26, 2025 No Comments

Relative effectiveness and cost-effectiveness of methods of androgen suppression in the treatment of advanced prostate cancer

This systematic review evaluated the effectiveness and cost-effectiveness of various androgen suppression therapies for advanced prostate cancer, comparing monotherapy options such as orchiectomy, luteinizing hormone-releasing hormone (LHRH) agonists, and antiandrogens to combined androgen blockade (CAB), while also examining the timing of therapy initiation (immediate vs. deferred). The study found that

Read More »
June 26, 2025 No Comments