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Tag: subchondral bone

Comparison efficacy of ESWT and Wharton’s jelly mesenchymal stem cell in early osteoarthritis of rat knee

This 2019 preclinical study evaluated the therapeutic effects of extracorporeal shockwave therapy (ESWT), Wharton’s jelly-derived mesenchymal stem cells (WJMSCs), and their combination in a rat model of early knee osteoarthritis (KOA). All treatment modalities significantly improved cartilage integrity and subchondral bone remodeling, as evidenced by pathological assessments, micro-CT, and immunohistochemical

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June 26, 2025 No Comments

Distribution of vitamin K2 in subchondral bone in osteoarthritic knee joints

This 2013 study analyzed vitamin K2 distribution in subchondral bone samples from 58 patients undergoing total knee arthroplasty due to osteoarthritis (OA). Using high-performance liquid chromatography, vitamin K2 concentrations were measured in medial and lateral femoral and tibial condyles. The medial condyles—typically more severely affected by OA—showed significantly lower vitamin

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June 26, 2025 No Comments