Striatal neuroprotection with methylene blue
This study investigated methylene blue’s (MB) neuroprotective effects in a rat model of striatal damage induced by rotenone (Rot), a mitochondrial toxin. Co-administration of MB significantly reduced the size of Rot-induced lesions, preserved cytochrome oxidase activity, and decreased oxidative stress in the striatum. Additionally, MB maintained functional connectivity in motor
June 26, 2025
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