Tag: stress resilience

Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases

This review explores the concept of adaptogens—herbal substances that enhance the body’s ability to adapt to stress and promote overall well-being—highlighting their effects on the neuroendocrine-immune system. Adaptogens show a biphasic dose-response, acting as mild stress-mimetics at low doses and having varying effects at higher doses. The review emphasizes the

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The Role of Nutrients in Protecting Mitochondrial Function and Neurotransmitter Signaling: Implications for the Treatment of Depression, PTSD, and Suicidal Behaviors

This systematic review explores how specific nutrients—such as B vitamins (B6, B9, B12), omega-3 fatty acids, vitamin D, vitamin C, magnesium, zinc, and antioxidants—support mitochondrial function and neurotransmitter signaling, both of which are disrupted in mood disorders like depression, PTSD, and suicidal behavior. The review highlights that correcting nutritional deficiencies

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