small molecules Archives - Well Referenced

Emerging treatments for ulcerative colitis: a systematic review

This 2017 systematic review analyzed 21 studies involving 11,524 adults to evaluate novel therapeutic options for ulcerative colitis (UC). Thirteen new treatments were identified. Vedolizumab and golimumab demonstrated superiority over placebo for both induction and maintenance therapy. Tofacitinib showed dose-dependent efficacy for induction therapy. Etrolizumab achieved higher clinical remission rates

June 26, 2025 No Comments

Autophagy Agents in Clinical Trials for Cancer Therapy: A Brief Review

This review article provides an overview of autophagy agents currently in clinical trials for cancer therapy. Autophagy, a cellular process that can influence cancer cell survival, has become a target for therapeutic intervention. The review highlights various autophagy modulators being tested, including small molecules, inhibitors, and gene therapy approaches. It

June 26, 2025 No Comments

Effects of small molecules on neurogenesis: Neuronal proliferation and differentiation

This 2024 review discusses how small molecules influence neurogenesis by modulating neuronal proliferation and differentiation. It highlights the role of neurotrophin mimetics, such as TrkA and TrkB receptor agonists, in promoting neuronal survival and growth. The article also examines the impact of epigenetic modifiers, like histone deacetylase inhibitors, on gene

June 26, 2025 No Comments

Tag: small molecules

Emerging treatments for ulcerative colitis: a systematic review

Autophagy Agents in Clinical Trials for Cancer Therapy: A Brief Review

Effects of small molecules on neurogenesis: Neuronal proliferation and differentiation