This 2021 review by Bittner et al. provides a comprehensive overview of Mohs micrographic surgery (MMS), a precise surgical technique for treating skin cancers. MMS involves the stepwise removal and microscopic examination of cancerous tissue, allowing for complete margin assessment while preserving healthy tissue. The review discusses indications for MMS,
This review article provides a detailed examination of the pharmacologic properties of topical agents used in the treatment of superficial skin cancers such as actinic keratoses and basal cell carcinoma. It reviews the mechanisms of action, pharmacokinetics, formulations, clinical indications, adverse effect profiles, and contraindications of approved agents like 5-fluorouracil,
This 2014 review evaluates the role of antioxidants in counteracting oxidative stress caused by ultraviolet radiation (UVR), a key factor in skin carcinogenesis. It explains how UVR leads to the generation of reactive oxygen species (ROS) that damage DNA, proteins, and lipids, accelerating skin aging and promoting cancer. The body’s
