Well Referenced

Tag: sexual satisfaction

Safety and efficacy of a testosterone metered-dose transdermal spray for treating decreased sexual satisfaction in premenopausal women: a randomized trial

This randomized controlled trial evaluated the safety and effectiveness of a testosterone metered-dose transdermal spray in premenopausal women aged 35–46 with decreased sexual satisfaction and low serum-free testosterone levels. A daily dose of 90-μL significantly increased satisfactory sexual events compared to placebo (2.48 vs. 1.70 events, p=0.04). The most common

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June 26, 2025 No Comments

Comparative efficacy of tadalafil once daily in men with erectile dysfunction who demonstrated previous partial responses to as-needed sildenafil, tadalafil, or vardenafil

This randomized controlled trial evaluated the efficacy and safety of once-daily tadalafil (TAD-OaD) in 590 men with erectile dysfunction (ED) who had partial responses to as-needed phosphodiesterase type-5 inhibitors (PDE5Is) such as sildenafil, tadalafil, or vardenafil. After a 4-week open-label PRN-PDE5I lead-in and a washout period, participants were randomized to

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June 26, 2025 No Comments

Effect of testosterone therapy versus other factors on the self-reported sexual satisfaction of premenopausal women

This observational study examined the effects of testosterone therapy compared to other factors on self-reported sexual satisfaction in premenopausal women. While testosterone therapy was found to influence libido and sexual function, other factors such as psychological well-being, relationship quality, and lifestyle choices played significant roles in determining overall sexual satisfaction.

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June 26, 2025 No Comments

Erectile function and assessments of erection hardness correlate positively with measures of emotional well-being, sexual satisfaction, and treatment satisfaction in men with erectile dysfunction treated with sildenafil citrate (Viagra)

This study analyzed data from 33 clinical trials involving nearly 10,000 men with erectile dysfunction (ED) treated with sildenafil citrate (Viagra) to assess its impact on erectile function, erection hardness, and psychosocial well-being. Findings indicated that improvements in erectile function, as measured by the International Index of Erectile Function (IIEF)

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June 26, 2025 No Comments

Toward personalized sexual medicine (part 2): testosterone combined with a PDE5 inhibitor increases sexual satisfaction in women with HSDD and FSAD, and a low sensitive system for sexual cues

This randomized controlled trial investigated the effectiveness of combining testosterone with a phosphodiesterase type 5 (PDE5) inhibitor to improve sexual satisfaction in women diagnosed with hypoactive sexual desire disorder (HSDD) and female sexual arousal disorder (FSAD) who exhibit low sensitivity to sexual cues. The study included 36 premenopausal women aged

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June 26, 2025 No Comments

Toward personalized sexual medicine (part 3): testosterone combined with a Serotonin1A receptor agonist increases sexual satisfaction in women with HSDD and FSAD, and dysfunctional activation of sexual inhibitory mechanisms

This randomized controlled trial investigated the efficacy of combining testosterone with a Serotonin1A (5-HT1A) receptor agonist to improve sexual satisfaction in women diagnosed with hypoactive sexual desire disorder (HSDD) and female sexual arousal disorder (FSAD) who exhibit heightened sexual inhibition. The study included 36 premenopausal women aged 35-55 and found

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June 26, 2025 No Comments

Meta-analysis of Results of Testosterone Therapy on Sexual Function Based on International Index of Erectile Function Scores

This meta-analysis evaluated the effects of testosterone therapy (TTh) on male sexual function using the International Index of Erectile Function (IIEF) scores. The results showed significant improvement in erectile function and sexual satisfaction in men with low testosterone, especially in those with initially low testosterone levels. Testosterone therapy was found

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June 26, 2025 No Comments

Hypoactive sexual desire disorder in menopausal women: a survey of Western European women

This observational study surveyed 2,467 European women aged 20-70 years to assess the prevalence of hypoactive sexual desire disorder (HSDD) among premenopausal, naturally menopausal, and surgically menopausal women. The analysis focused on 1,356 women with sexual partners, revealing that surgically menopausal women were significantly more likely to experience low sexual

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June 26, 2025 No Comments

Hypoactive sexual desire disorder in postmenopausal women: US results from the Women’s International Study of Health and Sexuality (WISHeS)

The study titled Hypoactive Sexual Desire Disorder in Postmenopausal Women: US Results from the Women’s International Study of Health and Sexuality (WISHeS), published in Menopause in 2006 (PMID: 16607098), examines the prevalence and impact of hypoactive sexual desire disorder (HSDD) in postmenopausal women in the United States. The research found

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June 26, 2025 No Comments

Disorders of orgasm and ejaculation in men

The article “Disorders of Orgasm and Ejaculation in Men” explores the diagnosis and management of common male sexual dysfunctions, including premature ejaculation, inhibited ejaculation, anejaculation, retrograde ejaculation, and anorgasmia. It highlights the psychological, neurological, and hormonal factors contributing to these conditions and emphasizes a multidisciplinary approach to treatment, incorporating both

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June 26, 2025 No Comments