Tag: serum biomarkers

Rapid and sensitive detection of interleukin-6 in serum via time-resolved lateral flow immunoassay

This study published in Analytical Biochemistry (DOI: 10.1016/j.ab.2019.113468) introduces a rapid, sensitive lateral flow immunoassay (LFIA) for detecting interleukin-6 (IL-6) levels in human serum. The assay, utilizing europium nanoparticles (Eu-NPs), demonstrated a detection range of 2–500 pg/mL and high sensitivity (0.37 pg/mL), with strong correlation (r = 0.9756, p <

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Oxidative stress biomarkers and lifestyles in Japanese healthy people

This observational study investigated the relationship between lifestyle factors and oxidative stress biomarkers in 135 healthy Japanese adults aged 20 to 69 years. The findings showed that smokers had significantly higher urinary 8-hydroxydeoxyguanosine (8-OHdG) levels (p < 0.05), indicating increased oxidative DNA damage, while individuals who engaged in regular physical

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