Well Referenced

Tag: serotonin receptors

Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs

This 2013 review discusses the pharmacology of serotonin (5-HT) receptors and highlights two selective 5-HT receptor subtype-targeted drugs: lorcaserin and pimavanserin. Lorcaserin is a 5-HT₂C receptor agonist approved for obesity treatment, promoting satiety through hypothalamic activation. Pimavanserin is a 5-HT₂A receptor inverse agonist approved for Parkinson’s disease psychosis, offering antipsychotic

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June 26, 2025 No Comments

Why All Migraine Patients Should Be Treated With Magnesium

This article emphasizes the critical role of magnesium in migraine management, advocating for its routine use in all migraine patients due to its potential to reduce migraine frequency and intensity. Magnesium is involved in several processes that may influence migraine pathogenesis, including cortical spreading depression, platelet aggregation, and serotonin receptor

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June 26, 2025 No Comments

Cannabidiol for the Treatment of Brain Disorders: Therapeutic Potential and Routes of Administration

This study explores the therapeutic potential of cannabidiol (CBD) for brain disorders, focusing on its interaction with multiple brain targets and evaluating alternative drug delivery methods to enhance its efficacy. Oral CBD administration is limited by slow absorption and low bioavailability due to first-pass metabolism, prompting interest in alternative delivery

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June 26, 2025 No Comments