Well Referenced

Tag: senolytics

Emerging Anti-Aging Strategies – Scientific Basis and Efficacy

This comprehensive review examines the scientific foundations and efficacy of emerging anti-aging strategies aimed at promoting healthier aging and mitigating age-related diseases. Key interventions discussed include caloric restriction, intermittent fasting, senolytics, sirtuin-activating compounds, NAD+ precursors, and stem cell therapies. The review highlights the mechanisms by which these strategies influence aging

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June 26, 2025 No Comments

Targeting aging and age-related diseases with vaccines

This 2024 review explores the potential of vaccines to address aging and associated chronic diseases. It discusses strategies targeting specific antigens linked to conditions such as Alzheimer’s disease, type II diabetes, hypertension, abdominal aortic aneurysm, atherosclerosis, osteoarthritis, fibrosis, and cancer. Additionally, the article examines emerging vaccines aimed at eliminating senescent

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June 26, 2025 No Comments

Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives

This 2017 review discusses the integration of geroprotective interventions, such as calorie restriction mimetics, autophagy inducers, and senolytics, into public health strategies. It highlights the potential of these interventions to extend healthspan and delay age-related diseases. The authors address challenges including regulatory hurdles, ethical considerations, and the need for robust

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June 26, 2025 No Comments

Senotherapeutics for mesenchymal stem cell senescence and rejuvenation

This review article explores the potential of senotherapeutics—specifically senolytics and senomorphics—in reversing mesenchymal stem cell (MSC) senescence to enhance regenerative therapies. Senolytics eliminate senescent cells, while senomorphics suppress harmful secretions from these cells (SASP), both working to rejuvenate MSCs and restore their regenerative function. These interventions have shown promise in

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June 26, 2025 No Comments