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Tag: senescent cells

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

This 2017 study by Jeon et al. investigated the role of senescent cells (SnCs) in the progression of post-traumatic osteoarthritis (OA) using a p16-3MR transgenic mouse model. Following anterior cruciate ligament transection (ACLT), SnCs accumulated in the articular cartilage and synovium. Selective elimination of these cells, either genetically or via

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June 26, 2025 No Comments

The effect of hyperbaric oxygen therapy on the pathophysiology of skin aging: a prospective clinical trial

This prospective clinical trial investigated the effects of hyperbaric oxygen therapy (HBOT) on skin aging in a healthy aging population. Participants underwent a three-month control period followed by three months of daily HBOT sessions, with skin biopsies taken at baseline, post-control, and post-HBOT. Findings showed significant increases in collagen density

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June 26, 2025 No Comments