Pantothenic Acid Deficiency as the Pathogenesis of Acne Vulgaris
This 1995 hypothesis by Dr. L.H. Leung proposes that acne vulgaris stems from a deficiency in pantothenic acid (vitamin B5), essential for synthesizing coenzyme A (CoA). CoA is crucial in fatty acid metabolism and hormone synthesis. A deficiency may impair lipid metabolism, leading to lipid accumulation in sebaceous glands and