Reliable and effective oxygen-ozone therapy at a crossroads with ozonated saline infusion and ozone rectal insufflation
This 2012 review by Bocci et al. discusses the clinical applications and safety considerations of oxygen-ozone therapy (OOT), particularly focusing on ozonated saline infusion and rectal insufflation. While intradiscal ozone injections have shown success in treating herniated discs, systemic applications like ozonated saline and rectal insufflation lack standardization and may