Well Referenced

Tag: regulatory T-cells

Human umbilical cord mesenchymal stem cell therapy for patients with active rheumatoid arthritis: safety and efficacy

This 2013 clinical study evaluated the safety and efficacy of human umbilical cord mesenchymal stem cells (UC-MSCs) in treating active rheumatoid arthritis (RA) unresponsive to conventional therapies. Involving 172 patients, the study compared outcomes between those receiving disease-modifying anti-rheumatic drugs (DMARDs) plus UC-MSCs and those receiving DMARDs alone. The UC-MSC

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June 26, 2025 No Comments

Vitamin A and D in allergy: from experimental animal models and cellular studies to human disease

This 2018 review explores the immunomodulatory roles of vitamins A and D in allergic diseases. Animal studies indicate that deficiencies in these vitamins exacerbate allergic symptoms and lung inflammation, while supplementation, particularly with vitamin D, can attenuate these effects. Active metabolites—retinoic acid (RA) from vitamin A and 1,25-dihydroxyvitamin D3 (VD3)

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June 26, 2025 No Comments

Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: a randomized pilot trial

This 2021 randomized pilot trial compared neoadjuvant everolimus plus letrozole (NET) with standard chemotherapy (FEC) in 40 postmenopausal women with ER-positive, HER2-negative breast cancer. The NET arm demonstrated a higher ultrasound response rate (65% vs. 40%) and better treatment completion (90% vs. 70%) compared to the FEC arm. Additionally, NET

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June 26, 2025 No Comments

The effects of oxygen-ozone therapy on regulatory T-cell responses in multiple sclerosis patients

This 2021 observational study titled “The Effects of Oxygen-Ozone Therapy on Regulatory T-Cell Responses in Multiple Sclerosis Patients” (Cell Biology International, DOI: [10.1002/cbin.11589*) investigated how medical ozone therapy impacts immune regulation in patients with multiple sclerosis (MS). The study found that ozone therapy significantly increased the frequency and suppressive function

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June 26, 2025 No Comments