Long-term Host Immune Response Trajectories Among Hospitalized Patients With Sepsis
This 2019 prospective cohort study published in JAMA Network Open (PMID: 31390038) analyzed long-term immune response trajectories in 483 sepsis survivors across 12 U.S. hospitals. Researchers tracked biomarkers of inflammation (hs-CRP) and immunosuppression (sPD-L1) over 12 months and identified two phenotypes: one with persistent hyperinflammation and immunosuppression, and another with
June 26, 2025
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