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Tag: reactive nitrogen species

Studies on Oxidants and Antioxidants with a Brief Glance at Their Relevance to the Immune System

This review explores the dual roles of oxidants and antioxidants in immune function. Reactive oxygen species (ROS) and reactive nitrogen species (RNS), while essential for pathogen defense and cellular signaling, can cause oxidative damage when unregulated. The body’s antioxidant systems, including enzymatic (e.g., superoxide dismutase, catalase) and non-enzymatic (e.g., vitamins

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June 26, 2025 No Comments

The Pivotal Role of Nitric Oxide: Effects on the Nervous and Immune Systems

This 2014 review explores nitric oxide (NO) as a critical signaling molecule with dual roles in physiological and pathological processes within the nervous and immune systems. In the nervous system, NO functions as a neurotransmitter and neuromodulator, influencing synaptic plasticity, neurovascular coupling, and mitochondrial biogenesis. Conversely, excessive NO production can

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June 26, 2025 No Comments

Free radicals, metals and antioxidants in oxidative stress-induced cancer

The article “Free radicals, metals and antioxidants in oxidative stress-induced cancer” explores the role of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in cellular processes, highlighting their dual nature in cancer development. While these species can function as secondary messengers in signaling pathways that promote oncogenesis, they can

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June 26, 2025 No Comments