Combination Therapy of Zonisamide and Bupropion for Weight Reduction in Obese Women: A Preliminary, Randomized, Open-Label Study
This 2007 preliminary, randomized, open-label study evaluated the efficacy of combining zonisamide and bupropion for weight loss in 18 obese women over 12 weeks. Participants were assigned to either zonisamide monotherapy (up to 400 mg/day) or a combination therapy with zonisamide (up to 400 mg/day) and bupropion (up to 200