Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation
This study investigates the effects of androgen deprivation followed by acute androgen stimulation on prostate cancer cells. The results demonstrate that this strategy selectively sensitizes androgen receptor (AR)-positive prostate cancer cells to ionizing radiation, enhancing the efficacy of radiation therapy. The study suggests that combining androgen manipulation with radiation therapy