This 2020 review examines the impact of high-protein diets on kidney function and longevity. High dietary protein intake can cause intraglomerular hypertension, leading to kidney hyperfiltration, glomerular injury, and proteinuria. While high-protein diets are popular for weight loss and type 2 diabetes management, evidence suggests that they may worsen renal
This 2012 randomized, double-blind, crossover study investigated the effects of α-lipoic acid (ALA) on endothelial function and proteinuria in 40 diabetic patients with stage I hypertension receiving quinapril 40 mg/day. Participants were treated for 8 weeks with either quinapril alone or quinapril plus ALA 600 mg/day. Results showed that the
This study examines the relationship between fibrinogen levels, lipids, and cardiovascular disease (CVD) risk in patients with chronic renal disease. Fibrinogen, a protein elevated during inflammation, was significantly higher in patients with renal disease compared to healthy controls. The study found a strong correlation between fibrinogen levels, diastolic blood pressure,
