Well Referenced

Tag: Prolactin

Targeting Hormones for Improving Cognition in Major Mood Disorders and Schizophrenia: Thyroid Hormones and Prolactin

This 2020 narrative review examines the role of thyroid hormones and prolactin in modulating cognitive function in patients with major mood disorders and schizophrenia. It highlights that cognitive impairment is a core symptom of these disorders and remains inadequately addressed by current treatments. Subclinical hypothyroidism and low free thyroxine (FT4)

Read More »
June 26, 2025 No Comments

Effect of Hypothyroidism on Female Reproductive Hormones

This 2016 prospective clinical study evaluated the effect of untreated primary hypothyroidism on reproductive hormone levels in women and the hormonal changes after levothyroxine therapy. The study included 59 women with hypothyroidism and 39 healthy controls. Results showed that hypothyroid patients had significantly elevated TSH and prolactin levels and significantly

Read More »
June 26, 2025 No Comments

Stimulation of the Growth Hormone (GH)-Insulin-Like Growth Factor I Axis by Daily Oral Administration of a GH Secretagogue (MK-677) in Healthy Elderly Subjects

This 1996 randomized, double-blind, placebo-controlled study by Chapman et al. investigated the effects of MK-677, an orally active growth hormone secretagogue, on the GH/IGF-I axis in healthy elderly individuals aged 64–81. Participants received daily doses of 2, 10, or 25 mg of MK-677 or placebo over two treatment periods (14

Read More »
June 26, 2025 No Comments

Hyperprolactinemia and sexual function in men: a short review

This 2003 review examines the impact of hyperprolactinemia (HPRL) on male sexual function. HPRL is associated with decreased libido, erectile dysfunction, and ejaculatory disorders. While traditionally attributed to reduced testosterone levels, evidence suggests that prolactin may also exert direct effects on central neurotransmitter systems, influencing sexual function independently of testosterone.

Read More »
June 26, 2025 No Comments