Medroxyprogesterone acetate-driven increase in breast cancer risk might be mediated via cross-talk with growth factors in the presence of progesterone receptor membrane component-1
This in vitro study explored the role of medroxyprogesterone acetate (MPA) in increasing breast cancer risk by enhancing cell proliferation in the presence of growth factors, particularly in cells overexpressing progesterone receptor membrane component-1 (PGRMC1). The findings revealed that MPA significantly increased cell proliferation when combined with growth factors, a
June 26, 2025
No Comments