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Tag: precision medicine

Recent Advances in Therapeutic Strategies for Triple-Negative Breast Cancer

This 2022 review comprehensively examines the latest therapeutic developments for triple-negative breast cancer (TNBC), a highly aggressive and heterogeneous subtype lacking hormone receptors and HER2 expression. The article outlines current treatment paradigms including chemotherapy, and highlights advancements such as immune checkpoint inhibitors (e.g., pembrolizumab, atezolizumab) for PD-L1-positive TNBC and PARP

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June 26, 2025 No Comments

Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicine

This 2018 review underscores the critical role of molecular testing for BRAF mutations, particularly the V600E variant, in guiding treatment strategies for advanced melanoma. Approximately 50% of advanced melanomas harbor BRAF mutations, making them amenable to targeted therapies with BRAF and MEK inhibitors, which have demonstrated significant long-term benefits. The

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June 26, 2025 No Comments