This study investigated the impact of hormone replacement therapy (HRT) on immune function in post-menopausal women. The findings indicated that HRT modulates immune responses, potentially restoring some aspects of immune function altered by menopause. Specifically, HRT was associated with changes in cytokine production and lymphocyte activity, suggesting a shift towards
This cohort study aimed to explore the impact of hormone replacement therapy (HRT) on C-reactive protein (CRP) levels in post-menopausal women with Type 2 diabetes (T2DM), highlighting that HRT use was associated with significantly elevated CRP levels, a marker of inflammation linked to cardiovascular disease. The study included 327 women,
This observational study examined the impact of estradiol (E2) levels on cognitive function during antidepressant treatment in 39 women with major depressive disorder (MDD), comparing pre-menopausal and post-menopausal groups. Over a 6-week period, cognitive function improved significantly across all participants (P=0.00001), but in post-menopausal women, higher E2 levels were strongly
