Role of magnesium in the pathogenesis and treatment of migraines
This 1998 review explores magnesium’s role in migraine pathogenesis and treatment. Magnesium deficiency may contribute to migraines by promoting cortical spreading depression, altering neurotransmitter release, and enhancing platelet aggregation. Clinical studies indicate that intravenous magnesium can provide rapid relief during acute migraine attacks, while oral supplementation may serve as a