Well Referenced

Tag: photodamage

Antioxidant Skincare Treatment for Hyperpigmented and Photodamaged Skin: Multi-Center, Open-Label, Cross-Seasonal Case Study

This 2023 multi-center, open-label study evaluated the efficacy of an enhanced vitamin C serum (eVCS) alone and in combination with a retinol-bakuchiol serum (RBS) in treating facial hyperpigmentation and photodamage. In vitro and ex vivo analyses demonstrated that the eVCS-RBS combination significantly reduced melanin production and increased collagen synthesis by

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June 26, 2025 No Comments

A Prospective, Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Efficacy, Safety, and Patient Satisfaction of Tretinoin 0.05% Lotion for Chest Rejuvenation

This 2022 randomized, double-blind, vehicle-controlled study assessed the efficacy, safety, and patient satisfaction of tretinoin 0.05% lotion for chest rejuvenation in 29 patients aged 37–66 years with Fitzpatrick skin types II–IV. Over 180 days, both the tretinoin and vehicle groups demonstrated 30–40% improvement in photodamage, as evaluated by blinded assessors.

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June 26, 2025 No Comments

An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin

This 2016 open-label, single-center clinical trial evaluated the efficacy and tolerability of a dual-product regimen comprising a 0.5% encapsulated retinol treatment and a moisturizer containing 30% tetrahexyldecyl ascorbate (vitamin C), along with vitamin E and coenzyme Q10, in 44 women aged 35–60 with mild-to-moderate facial hyperpigmentation and photodamage over 12

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June 26, 2025 No Comments