This 2012 study investigated the effects of mild cold exposure and the sympathomimetic drug ephedrine on brown adipose tissue (BAT) activation in 10 healthy adults. Using ^18F-fluorodeoxyglucose PET-CT scans, researchers found that cold exposure significantly increased BAT activity in all participants, while ephedrine did not stimulate BAT despite increasing heart
This 2014 clinical investigation explored how thyroid hormones influence brown adipose tissue (BAT) activity in euthyroid human subjects using PET-CT imaging. Participants with higher circulating thyroid hormone levels, especially triiodothyronine (T3), demonstrated significantly increased glucose uptake in BAT, indicating heightened thermogenic activity. The study confirmed that thyroid hormones directly stimulate
This 2009 study assessed radiation exposure and associated cancer risk from whole-body 18F-FDG PET/CT scans using three CT protocols. Effective doses ranged from 13.45 to 32.18 mSv, depending on the protocol and patient sex. Lifetime attributable cancer risk (LAR) was higher in younger individuals and in the Hong Kong population
