Magnesium inhibits norepinephrine release by blocking N-type calcium channels at peripheral sympathetic nerve endings
This in vitro and animal study explored the role of magnesium in regulating blood pressure by examining its effect on norepinephrine release from sympathetic nerve endings. Using hypertensive and normotensive rat models, as well as cultured PC12 cells, researchers found that magnesium significantly inhibited norepinephrine release—reducing it by 51% in
June 26, 2025
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