Tag: PBDEs

Exposures, Mechanisms, and Impacts of Endocrine-Active Flame Retardants

This 2014 review examines the endocrine and neurodevelopmental effects of flame retardants, focusing on tris(1,3-dichloro-isopropyl) phosphate (TDCPP), Firemaster® 550 (FM550), and polybrominated diphenyl ethers (PBDEs). These chemicals, commonly used in consumer products like polyurethane foam, have led to widespread indoor exposure. PBDEs and their metabolites primarily disrupt thyroid function due

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Exposure to endocrine-disrupting chemicals in the USA: a population-based disease burden and cost analysis

This study quantified the health and economic impacts of endocrine-disrupting chemical (EDC) exposure in the U.S., estimating annual costs exceeding $340 billion, or over 2.3% of GDP. Utilizing epidemiological and toxicological models, the research identified significant associations between EDCs and various health outcomes. Key findings include: Polybrominated diphenyl ethers (PBDEs)

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