Coenzyme Q10 and Heart Failure: A State-of-the-Art Review
The review article examines the role of Coenzyme Q10 (CoQ10) in the management of chronic heart failure (HF), emphasizing its biochemical function in mitochondrial energy production and antioxidant activity. The Q-SYMBIO trial demonstrated that CoQ10 supplementation significantly reduced cardiovascular mortality by 42% (p=0.026) and all-cause mortality by 43% (p=0.036) over