Tag: pathogenesis

Lyme Disease in Humans

This 2021 comprehensive review article provides an in-depth analysis of Lyme disease, a tick-borne illness caused by Borrelia burgdorferi sensu lato complex. The disease is prevalent across the Northern Hemisphere and is transmitted by ticks from the Ixodes ricinus complex. The article discusses the increasing global incidence of Lyme disease,

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Involvement of inflammation in Alzheimer’s disease pathogenesis and therapeutic potential of anti-inflammatory agents

This review explores the role of neuroinflammation in Alzheimer’s disease (AD) and the potential therapeutic application of anti-inflammatory agents. It highlights how astrocytes, microglia, peripheral immune cells, and microRNAs contribute to neuroinflammatory responses that exacerbate AD progression. Anti-inflammatory drugs may offer neuroprotection by modulating these pathways, potentially slowing disease progression

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