Tag: osteocalcin

Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease

This review article explores the beneficial effects of exercise on brain-derived neurotrophic factor (BDNF) expression in Alzheimer’s disease (AD). The study discusses how exercise increases BDNF levels through peripheral signals such as osteocalcin, FNDC5/irisin, and lactate, which promote cognitive function, neurogenesis, and synaptic health. The article emphasizes the protective role

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