Tag: Ophthalmology

Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Age-Related Macular Degeneration

This 2020 study evaluated the safety and efficacy of autologous bone marrow-derived stem cells (BMSCs) in 32 eyes from patients aged 69–90 with dry age-related macular degeneration (AMD). BMSCs were administered via retrobulbar, subtenons, intravitreal, subretinal, and intravenous routes. After treatment, 63% of eyes showed improvement in visual acuity, 34%

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Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Stargardt Disease

The SCOTS and SCOTS2 trials evaluated the safety and efficacy of autologous bone marrow-derived stem cells (BMSCs) in 34 eyes from patients with Stargardt Disease. BMSCs were administered via retrobulbar, subtenons, intravitreal, subretinal, and intravenous routes. After one year, 61.8% of eyes showed visual improvement, 23.5% remained stable, and 14.7%

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A Double-Blind, Cross-Over, Study of Oral N-Acetylcysteine in Sjögren’s Syndrome

This 1986 double-blind, cross-over trial evaluated the efficacy of oral N-acetylcysteine (NAC) in 26 patients with primary or secondary Sjögren’s syndrome over a four-week period. Baseline assessments revealed significantly elevated salivary lactoferrin levels and decreased tear lysozyme levels compared to healthy controls. Following NAC treatment (200 mg three times daily),

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